Method for preparing technetium- and rhenium-carborane...

Details Method for preparing technetium- and rhenium-carborane... Method for preparing technetium- and rhenium-carborane...

C - Chemistry, Metallurgy

07

F

C07F 13/00 (2006.01) A61K 51/00 (2006.01) A61K 51/04 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2348831

The present invention relates to a new method for the preparation of radiopharmaceuticals based on technetium and rhenium. The method involves the reaction of an [M(CO)3X3]2- salt, wherein M is selected from a radioisotope of rhenium and technetium and X is selected from Cl and Br, with a nido-dicarbollide dianion of the formula [nido-(C2B9H11)]2- and functional derivatives thereof. The method has been shown to be applicable to the preparation of radiopharmaceuticals at the tracer level.

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