Method for preparing transgenic non-human mammalian organs...

Details Method for preparing transgenic non-human mammalian organs... Method for preparing transgenic non-human mammalian organs...

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A01K 67/027 (2006.01) A61K 35/12 (2006.01) C07K 16/28 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) C12N 9/10 (2006.01) C12N 15/54 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2258872

The use of nucleotide sequences coding for antibodies to any molecule involved in a graft versus host reaction (hereinafter anti-molecule antibodies), for preparing transgenic cells or organs of non-human mammals, wherein said molecules at least partially form immune complexes with said anti-molecule antibodies, such that the activity of said molecules in graft versus host reactions is at least partially inhibited, said transgenic cells or organs of non-human mammals being intended for transplantation into a patient, is disclosed.

L'invention a pour objet l'utilisation de séquences nucléotidiques codant pour des anticorps dirigés contre toute molécule impliquée dans un phénomène de rejet de greffe (encore désignés ci-après anticorps anti-molécules), pour la préparation de cellules transgéniques, ou organes transgéniques, de mammifères non humains, au sein desquels lesdites molécules forment en totalité ou en partie des complexes immuns avec lesdits anticorps anti-molécules, de telle sorte que l'activité desdites molécules dans les phénomènes de rejet de greffe soit totalement ou partiellement inhibée, lesdites cellules ou lesdits organes transgéniques de mammifères non humains étant destinés à être greffés chez un patient.

Affiliated with

Also associated with

Rating

Method for preparing transgenic non-human mammalian organs... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for preparing transgenic non-human mammalian organs..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for preparing transgenic non-human mammalian organs... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1882018