Method for preparing water soluble polypeptides

Details Method for preparing water soluble polypeptides Method for preparing water soluble polypeptides

C - Chemistry, Metallurgy

12

N

530/13, 195/1.22

C12N 15/12 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2006475

-33- METHOD FOR PREPARING WATER SOLUBLE POLYPEPTIDES Abstract of the Disclosure Methods are provided for the preparation in recombinant host cells of biologically active soluble variants of discretely encoded, heteromultimer polypeptide receptors. Such variants are synthesized by the secretion from recombinant transformants of transmembrane-modified heteromultimer receptors. Preferred receptors are extracellular matrix, cell surface, or plasma protein-binding receptors such as GPIIb-IIIa.

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