Method for preventing and treating peripheral neuropathy by...

A - Human Necessities – 61 – K

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A61K 31/135 (2006.01) A61K 31/137 (2006.01) A61K 31/337 (2006.01) A61K 31/475 (2006.01) A61K 33/24 (2006.01) A61K 45/00 (2006.01)

Patent

CA 2244253

The present invention is directed to methods for alleviating the symptoms associated with peripheral neuropathy. The neuropathy may be the result of a genetically inherited condition, systemic disease or exposure to a toxic agent. A reduction or elimination of symptoms is obtained by administering the drug selegiline. The invention is also directed to a method for treating patients with cancer by administering a chemotherapeutic agent known to have a toxic affect on peripheral nerves together with selegiline.

Méthodes destinées à soulager les symptômes associés à la neuropathie périphérique. Cette neuropathie peut être causée par un état génétiquement transmis, une maladie systémique ou l'exposition à un agent toxique. On obtient une réduction ou une suppression des symptômes en administrant le médicament sélégiline. L'invention se rapporte également à une méthode de traitement de patients cancéreux par administration d'un agent chimiothérapeutique connu pour son effet toxique sur les nerfs périphériques, en association avec la sélégiline.

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