Method for preventing xenograft transplant rejection using...

A - Human Necessities – 61 – K

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A61K 41/00 (2006.01) A61K 35/28 (2006.01) A61K 35/32 (2006.01) A61K 35/39 (2006.01)

Patent

CA 2346644

Donor material from a xenogeneic source is modified to enhance its survival time in a recipient by treating the donor material using low-dose photodynamic therapy (PDT). The donor material, such as an organ or cell suspension, is treated with a photosensitizer and irradiated in a low-dose protocol before transplantation into a xenogeneic recipient.

Un matériel de donneur provenant d'une source xénogène est modifié de sorte que sa durée de survie soit augmentée dans un receveur, par traitement de celui-ci au moyen d'une thérapie photodynamique à faibles doses. Le matériel de donneur, tel qu'un organe ou une suspension cellulaire, est traité à l'aide d'un photosensibilisant et irradié dans un protocole à faibles doses avant la transplantation dans un receveur xénogène.

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