C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/211, 260/284
C07D 215/42 (2006.01) C07D 215/233 (2006.01) C07D 215/36 (2006.01) C07D 215/38 (2006.01) C07D 215/48 (2006.01) C07D 401/06 (2006.01) C07D 409/06 (2006.01)
Patent
CA 1314888
ABSTRACT OF THE DISCLOSURE The present invention relates to novel 1-acyl-2,3-dihydro-4(1H)-quinolinone-4-oxime derivatives, processes for producing said derivatives, intermediate compounds, i.e. novel 1- acyl- 2,3- dihydro- 4(1H) - quinolinone derivatives, to produce said derivatives, processes to produce said intermediate compounds, and compositions containing said derivatives with potent diuretic activity that can be used for treating and/or preventing hypertension, oedema and/or for removing ascites. The novel 1-acyl-2,3-dihydro-4(1H)-quinolinone- 4- oxime derivatives contain O- sulfate, O - mesylate, O- methylphospate and O- carboxymethyl ester, especially O- sulfate of 4-oxime.
536174
Haga Akinori
Kato Kazuo
Mochida Ei
Tokunaga Hiroki
Uemura Akio
Borden Ladner Gervais Llp
Hodogaya Chemical Co. Ltd.
Mochida Pharmaceutical Co. Ltd.
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