C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01)
Patent
CA 2576299
Disclosed is a method for producing 2-(4-methyl-2-phenylpiperazine-1-yl)-3- cyanopiridine which contains a process for reacting 1-methyl-3- phenylpiperazine with 2-chloro-3-cyanopiridine in a polar non-protic organic solvent in the presence of an organic base and without the presence of an alkali metal halide.
On divulgue une méthode de production de 2-(4-méthyl-2-phénylpipérazine-1-yl)-3-cyanopyridine qui contient un procédé de réaction de 1-méthyl-3-phénylpipérazine avec de la 2-chloro-3-cyanopyridine dans un solvant organique non protique polaire en présence d~une base organique et sans la présence d~un halogénure de métal alcalin.
Inoue Haruyuki
Shimokawa Kaoru
Yamamoto Tomiaki
Marks & Clerk
Sumitomo Chemical Company Limited
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