C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/275.5, 260/2
C07D 215/22 (2006.01) C07D 491/052 (2006.01)
Patent
CA 1308415
ABSTRACT A method for producing a 2,4-dihydroxyquinoline derivative of the formula: Image (II) wherein each of R1, R2, R3 and R4 is a hydrogen atom, a lower alkyl group, a lower alkoxy group or a halogen atom, and its tautomer, which comprises cyclizing an aryl malonic acid amide ester derivative of the formula: Image (I) wherein R1, R2, R3 and R4 are as defined above, and R5 is a lower alkyl group, by means of polyphosphoric acid.
563235
Imaki Naoshi
Oishi Mari
Takuma Yuki
Imaki Naoshi
Mitsubishi Chemical Industries Limited
Mitsubishi Kasei Corporation
Oishi Mari
Smart & Biggar
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