C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 3/08 (2006.01) C07H 3/02 (2006.01)
Patent
CA 2492558
The present invention relates to a economic synthetic method of 2-deoxy-L- ribose from 2-deoxy-D-ribose with easy reaction, separation and purification. The present invention consists of four(4) steps including protection, activation 3-and 4-OH groups, inversion and deprotection step. In respect to the cost for equipment, reagent and operation, by the present invention, 2- deoxy-L-ribose can be produced more economically because the invention uses 2- deoxy-L-ribose which is abundant in nature and easily synthesized from D- glucose, and adopt simple and yielding process.
L'invention concerne une méthode économique pour synthétiser du 2-désoxy-L-ribose à partir de 2-désoxy-D-ribose, par le biais d'une réaction, d'une séparation et d'une purification faciles. L'invention comprend 4 étapes : une étape de protection, une étape d'activation de 3 ou 4 groupes OH, une étape d'inversion et une étape de déprotection. L'invention permet d'obtenir un coût réduit pour l'équipement, les réactifs et la mise en oeuvre économique de la production de 2-désoxy-L-ribose, car l'invention fait appel à du 2-désoxy-L-ribose qui est abondant à l'état naturel, qui est facilement synthétisé à partir de D-glucose, et à un processus simple et à haut rendement.
Jeon Byoung-Chan
Kang Jae-Sung
Lee Sang-Dae
Shin Jeong-Ah
Yun Mi-Hong
Ridout & Maybee Llp
Samchully Pharm. Co. Ltd.
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