C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 59/00 (2006.01) C07C 51/377 (2006.01) C07C 51/44 (2006.01) C07C 57/02 (2006.01) C12N 9/78 (2006.01) C12P 7/40 (2006.01) C12P 7/42 (2006.01) C12P 7/52 (2006.01)
Patent
CA 2475271
The present invention relates to a method for producing 2-hydroxyisobutyric acid where acetone cyanohydrin is converted to 2-hydroxyisobutyric acid using an enzyme catalyst having nitrilase activity, or having a combination of nitrile hydratase and amidase activities. The invention also encompasses production of methacrylic acid wherein the 2-hydroxyisobutyric acid produced with the catalyst described is dehydrated to produce methacrylic acid.
L'invention concerne un procédé de production de l'acide 2-hydroxyisobutyrique qui consiste à transformer la cyanohydrine d'acétone en acide 2-hydroxyisobutyrique au moyen d'un catalyseur enzymatique ayant une activité de nitrilase, ou une combinaison d'activités de nitrile hydratase et de nitrile amidase. L'invention concerne également la production d'acide méthycrylique au cours de laquelle l'acide 2-hydroxyisobutyrique produit à l'aide dudit catalyseur est déshydraté pour obtenir de l'acide méthacrylique.
Chauhan Sarita
Dicosimo Robert
Fallon Robert D.
Gavagan John E.
Manzer Leo E.
Bennett Jones Llp
E. I. Du Pont de Nemours And Company
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