Method for producing 4-pentafluoride-sulfanyl-benzoylguanidines

Details Method for producing 4-pentafluoride-sulfanyl-benzoylguanidines Method for producing 4-pentafluoride-sulfanyl-benzoylguanidines

C - Chemistry, Metallurgy

07

C

C07C 381/00 (2006.01)

Patent

CA 2545291

The invention relates to a method for producing 4-pentafluoride-sulfanyl- benzoylguanidines of formula (I) wherein groups from R1 to R4 correspond to meanings given in claims. The compounds of the formula (I) constitute NHE1 inhibitors and can be used for curing cardiovascular diseases.

L'invention concerne un procédé de production de 4-pentafluorosulfanylbenzoylguanidines correspondant à la formule (I), dans laquelle les groupes R1 à 4 correspondent à la définition donnée dans les revendications. Ces composés correspondant à la formule (I) constituent des inhibiteurs de NHE1 et peuvent, par exemple, être utilisés pour le traitement de maladies cardio-vasculaires.

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