Method for producing a hydroxyalkyl starch derivative with...

Details Method for producing a hydroxyalkyl starch derivative with... Method for producing a hydroxyalkyl starch derivative with...

C - Chemistry, Metallurgy

08

B

C08B 31/12 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2707806

A method of producing a hydroxyalkyl starch (HAS) derivative, comprising a) reacting optionally oxidized hydroxyalkyl starch with a compound (D) comprising at least two functional groups -O-NH2 or a salt thereof, and b) reacting the hydroxyalkyl starch derivative obtained in step a) with a compound (L) comprising at least two functional groups W1 and W2 independently selected from the group consisting of an aldehyde group, a suitably protected aldehyde group, a keto group, and a suitably protected keto group.

La présente invention concerne un procédé de production d'un dérivé d'amidon hydroxyalkylé (HAS), comprenant les étapes consistant a) à faire réagir un amidon hydroxyalkylé, éventuellement oxydé, avec un composé (D) comprenant au moins deux groupes fonctionnels -O-NH2 ou son sel, et b) à faire réagir le dérivé d'amidon hydroxyalkylé obtenu à l'étape a) avec un composé (L) comprenant au moins deux groupes fonctionnels W1 et W2, choisis, indépendamment l'un de l'autre, dans le groupe constitué d'un groupe aldéhyde, d'un groupe aldéhyde convenablement protégé, d'un groupe céto et d'un groupe céto convenablement protégé.

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