Method for producing acetophenone derivatives

C - Chemistry – Metallurgy – 07 – C

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260/578.2

C07C 225/16 (2006.01)

Patent

CA 1211126

ABSTRACT There are disclosed an improvement in the method for producing an acetophenone derivative of the formula: Image wherein R is a protective group for hydroxy group, which comprises condensing a halogenoacetophenone deri- vative of the formula: Image wherein X is a halogen atom and R is as defined above, with 3,4-dimethoxyphenethylamine in a two-phase solvent system of a non-hydrophilic organic solvent and water in the presence of an acid acceptor.

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