Method for producing actinium-225 and isotopes of radium and...

G - Physics – 21 – G

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G21G 1/10 (2006.01) G21K 5/08 (2006.01) H05H 6/00 (2006.01)

Patent

CA 2738308

The invention relates to nuclear technology and radiochemistry, namely, to the production and recovery of radionuclides for medicinal purposes. The process for producing actinium-235 and radium isotopes comprises the irradiation of a bulk thorium metal monolith 2 to 30 mm thick, enclosed in an air-tight shell made of a material that does not react with thorium, with a high-intensity beam of accelerated charged particles. The irradiated metallic thorium is withdrawn from the shell and then either heated with lanthanum addition and radium sublimation, or dissolved in nitric acid and the actinium-235 is recovered by extraction. Targets for implementing the process are metallic thorium monoliths 2 to 30 mm thick enclosed into air-tight shells made of various materials that do not react with thorium.

Linvention se rapporte au domaine des techniques nucléaires et de la radiochimie, et concerne plus particulièrement la production et la séparation de radionucléides à des fins médicales. Le procédé de production dactinium 225 et disotopes de radium consiste à irradier un monolithe massif de thorium métallique dune épaisseur de 2 à 30 mm, qui est enfermé dans une enceinte hermétique faite dun matériau ninteragissant pas avec le thorium, avec un courant de particules chargées et accélérées dune grande intensité. Le thorium métallique irradié est extrait de lenceinte, puis est soit chauffé parallèlement à laddition de lanthane avec distillation de radium, soit dissous dans de lacide nitrique, après quoi lactinium 225 est obtenu par extraction. La cible permettant de réaliser ce procédé se présente sous forme de monolithes de thorium métallique ayant une épaisseur de 2 à 30 mm qui sont enfermés dans une enceinte hermétique faite de différents matériaux ninteragissant pas avec le thorium.

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