A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) C07K 16/06 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2266848
An IgM-containing immunoglobulin solution is treated with a protease in a method for producing an immunoglobulin solution that is adequate for intravenous administration and having an Igm proportion higher than 5 weight % with respect to the immunoglobulin proportion. The iv-tolerant preparation obtained is characterized by not being chemically modified and by having low anticomplementary ACA activity.
L'invention concerne un procédé de production d'une solution d'immunoglobulines contenant une proportion d'IgM de plus de 5 % en poids par rapport à la proportion d'immunoglobulines et convenant à une administration intraveineuse. On traite une solution d'immunoglobulines contenant des IgM avec une protéase. La préparation ainsi obtenue, tolérée en administration intraveineuse, est caractérisée en ce qu'elle n'est pas chimiquement modifiée et en ce qu'elle présente une faible ACA (activité anticomplémentaire).
Fetherstonhaugh & Co.
Rotkreuzstiftung Zentrallaboratorium Blutspendedienst Srk
Zlb Bioplasma Ag
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