Method for producing anti-idiotypic antibodies

Details Method for producing anti-idiotypic antibodies Method for producing anti-idiotypic antibodies

C - Chemistry, Metallurgy

12

P

C12P 21/00 (2006.01) C07K 16/42 (2006.01) C12N 15/09 (2006.01) C12P 21/08 (2006.01) A01K 67/027 (2006.01)

Patent

CA 2607709

The present invention relates to a use of a non-human animal transgenic for an exogenous antibody for generating anti-idiotypic antibodies and a method for generating anti-idiotypic antibodies comprising a) creating a non-human animal transgenic for an exogenous antibody, b) inducing an immune response in said transgenic non- human animal against an antibody of interest, whereby the antibody of interest comprises the same species-specific isotype as the exogenous antibody, and c) generating antibodies directed against the idiotypic part of the antibody of interest.

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