C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 13/08 (2006.01) C12N 1/00 (2006.01) C12N 15/09 (2006.01)
Patent
CA 2583514
A process for producing a basic substance according to a fermentation technique, including culturing a microbe having the potency of producing a basic substance in a fermentation tank containing a liquid culture medium to thereby produce and accumulate the basic substance in the culture medium, characterized in that during at least a partial period of the entire culturing step, the ammonia concentration of the culture medium is regulated so as to fall within a given concentration range, thereby reducing the amount of sulfate ion and/or chloride ion used as a counter ion of the basic substance.
L~invention concerne un procédé de fabrication d~une substance de base selon une technique de fermentation, comprenant la mise en culture d~un microbe ayant le pouvoir de produire une substance de base dans un réservoir de fermentation contenant un milieu de culture liquide pour ainsi produire et accumuler la substance de base dans le milieu de culture, caractérisé en ce que pendant au moins une période partielle de la phase de mise en culture toute entière, la concentration d~ammoniac du milieu de culture est régulée pour entrer dans une fourchette de concentrations donnée, réduisant ainsi la quantité d'ion de sulfate et/ou d~ion de chlorure servant de contre-ion de la substance de base.
Sugimoto Shinichi
Takeshita Ryo
Ajinomoto Co. Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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