Method for producing calcium pantothenate

Details Method for producing calcium pantothenate Method for producing calcium pantothenate

C - Chemistry, Metallurgy

07

C

C07C 231/24 (2006.01) A61K 31/197 (2006.01) A61P 3/02 (2006.01) A61P 17/00 (2006.01) A61P 29/00 (2006.01) C07C 235/12 (2006.01)

Patent

CA 2356166

A method for producing nondeliquescent, crystalline calcium pantothenate comprising the steps of: (1) stirring a supersaturated aqueous solution containing calcium pantothenate in a proportion of 60 % (W/W) or more with, for example, a wet crusher to prepare a suspension of crystals; and (2) drying the suspension. The method can be used for efficiently producing nondeliquescent, crystalline calcium pantothenate which is substantially free of an organic solvent.

Un procédé de production de pantothénate de calcium non déliquescent cristallin comprend les étapes consistant (1) à agiter une solution aqueuse supersaturée contenant du pantothénate de calcium en une proportion de 60 % en poids (W/W) ou davantage avec, par exemple, un broyeur humide afin de préparer une suspension de cristaux, et (2) à sécher la suspension. Le procédé peut être utilisé pour produire efficacement du pantothénate de calcium non déliquescent cristallin sensiblement exempt de solvant organique.

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