Method for producing chiral .alpha.,.beta.-epoxy ketones

C - Chemistry – Metallurgy – 07 – D

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D 301/12 (2006.01)

Patent

CA 2717558

A process is claimed for the enantioselective epoxidation of .alpha.,.beta.- unsaturated ketones, in which a compound of the general formula I, (see formula I) is reacted with an oxidizing agent to form .alpha.,.beta.-epoxy ketones of the general formula II, (see formula II) in which R1, R2, R3 are as defined above. The .alpha.,.beta.-epoxy ketones of the general formula II can be obtained in good yields and outstanding enantioselectivities from .alpha.,.beta.-unsaturated ketones of the general formula I by epoxidation with hydrogen peroxide in the presence of a chiral catalyst, such as amino compounds and their acid addition salts.

L'invention concerne un procédé d'époxydation énantiosélective de cétones a,ß-insaturées, suivant lequel on fait réagir un composé de la formule générale (I) avec un agent oxydant, avec formation d'a,ß-époxycétones de la formule générale (II) dans laquelle R1, R2, R3 sont tels que définis ci-dessus. Les a,ß-époxycétones de la formule générale (II) peuvent être obtenues avec de bons rendements et d'excellentes énantiosélectivités à partir de cétones a,ß-insaturées de la formule générale (I) par époxydation avec du peroxyde d'hydrogène en présence d'un catalyseur chiral tel que des composés aminés et leurs sels d'addition avec un acide.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Method for producing chiral .alpha.,.beta.-epoxy ketones does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for producing chiral .alpha.,.beta.-epoxy ketones, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for producing chiral .alpha.,.beta.-epoxy ketones will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1628178

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.