Method for producing cytosine nucleosides compounds

Details Method for producing cytosine nucleosides compounds Method for producing cytosine nucleosides compounds

C - Chemistry, Metallurgy

07

H

C07H 19/06 (2006.01) C12N 9/10 (2006.01) C12P 19/34 (2006.01) C12P 19/38 (2006.01)

Patent

CA 2380804

The invention provides a method for producing a cytosine nucleoside compound from pentose-1-phosphate and cytosine or a derivative thereof using a nucleoside phosphorylase reactive to cytosine or a bacterium having the enzyme activity. The invention also provides a method for specifically reducing an activity to degrade the substrates or the product, resulting in efficient production of the cytosine nucleoside compound. According to the invention, little by-product is produced in producing cytonucleocide compounds.

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