Method for producing enantiomer-free 6,8 dihydroxy octanoic...

C - Chemistry – Metallurgy – 07 – C

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C07C 67/31 (2006.01) C07C 69/675 (2006.01) C07C 69/716 (2006.01) C07D 303/32 (2006.01) C07D 303/42 (2006.01) C07D 339/04 (2006.01)

Patent

CA 2417269

The invention relates to a method for producing compounds of general formula (I) wherein R1 represents a C1-C20 alkyl group, a C3-C12 cycloalkylgroup, a C7- C12 aralkyl group, or a mono or bicyclic aryl group. A ketone of formula (II) wherein R1 has the aforementioned meaning is asymmetrically hydrogenated.

L'invention concerne un procédé pour la production de composés de formule générale (I), dans laquelle R?1¿ représente un groupe alkyle C¿1?-C¿20?, un groupe cycloalkyle C¿3?-C¿12?, un groupe aralkyle C¿7?-C¿12? ou un groupe aryle monocyclique ou bicyclique. Le procédé selon l'invention est caractérisé en ce qu'on hydrogène de manière asymétrique une cétone de formule (II) dans laquelle R?1¿ a la signification précédente.

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