Method for producing factor viii:c-type proteins

Details Method for producing factor viii:c-type proteins Method for producing factor viii:c-type proteins

C - Chemistry, Metallurgy

12

N

195/128, 195/1.3

C12N 15/57 (2006.01) C07K 14/755 (2006.01) C12N 9/64 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1331157

IMPROVED METHOD FOR PRODUCING FACTOR VIII:c-TYPE PROTEINS Abstract of the Disclosure An improved method for producing Factor VIII:c-type proteins is disclosed which involves culturing mammalian cells which are capable of expressing the protein. In accordance with this invention the cells are cultured in a medium containing an effective amount of a substance comprising (a) von Willebrand Factor (VWF), (b) a phospholipid or phospholipid mixture, or a mixture of (a) and (b).

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