Method for producing high-purity prasugrel hydrochloride

Details Method for producing high-purity prasugrel hydrochloride Method for producing high-purity prasugrel hydrochloride

C - Chemistry, Metallurgy

07

D

C07D 495/04 (2006.01) A61K 31/4365 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2679925

The object is to provide prasugrel hydrochloride or the like having a reduced CATP content. Specifically disclosed is a process for producing prasugrel hydrochloride shown by the scheme below, wherein the temperature at which a chlorinating agent is added dropwisely or added in step (i) and the reaction temperature after the dropwise addition or addition of the chlorinating agent are adjusted to lower temperatures. Step i Step ii Step iii Step iv wherein R represents a protective group for a hydroxy group.

La présente invention concerne un procédé de production de chlorhydrate de prasugrel ou analogue présentant une teneur réduite en CATP. Cette invention concerne spécifiquement un procédé de production de chlorhydrate de prasugrel représenté par le schéma, la température à laquelle un agent de chloration est ajouté au goutte à goutte ou ajouté à l'étape (i) et la température de réaction après l'ajout au goutte à goutte ou l'ajout de l'agent de chloration étant réduites à des températures inférieures. Dans les formules, R désigne un groupe protecteur pour un groupe hydroxy.

Affiliated with

Also associated with

Rating

Method for producing high-purity prasugrel hydrochloride does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for producing high-purity prasugrel hydrochloride, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for producing high-purity prasugrel hydrochloride will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2058753