Method for producing hyaluronic acid

C - Chemistry – Metallurgy – 12 – P

Patent

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C12P 19/26 (2006.01) C08B 37/00 (2006.01)

Patent

CA 2732092

It is intended to provide a simple method for producing hyaluronic acid at a high yield. Further, it is also intended to provide a method for producing hyaluronic acid in a short period of time. The invention provides a method for producing hyaluronic acid including a step of culturing a microorganism having the capability to produce hyaluronic acid and a step of adding glutamine and arginine to a culture medium during late logarithmic growth phase of the microorganism.

Cette invention concerne une méthode de production simple dacide hyaluronique à un rendement élevé. Linvention concerne aussi une méthode de production dacide hyaluronique en un laps de temps réduit. Selon linvention, les méthodes de production dacide hyaluronique comprennent les étapes consistant à mettre en culture un micro-organisme ayant une aptitude à produire lacide hyaluronique, puis à ajouter de la glutamine et de larginine à une solution de culture à une étape de croissance logarithmique du micro-organisme tardive.

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