Method for producing lamotrigine from...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 253/06 (2006.01) C07C 251/30 (2006.01) C07C 255/61 (2006.01) C07C 257/14 (2006.01) C07C 281/18 (2006.01) C07C 291/02 (2006.01) C07D 253/075 (2006.01)

Patent

CA 2417435

The present invention relates to a method for producing 3,5-diamino-6-(2,3- dichlorophenyl)-1,2,4-triazine (lamotrigine) by cyclization reaction from .alpha.-oxo-2,3- dichlorophenylacetamidino-aminoguanidino-hydrazone.

L'invention concerne un procédé de fabrication de 3,5-diamino-6(2,3-dichlorphényl)-1,2,4-triazine (lamotrigine) par réaction avec fermeture du cycle, à partir de alpha -oxo-2,3-dichlorphénylacétamidino-aminoguanidino-hydrazone.

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