C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 51/09 (2006.01) A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 31/20 (2006.01) A61K 31/201 (2006.01) A61K 31/366 (2006.01) A61K 47/00 (2006.01)
Patent
CA 2294724
The invention relates to a method for producing medicaments containing HMG-CoA- reductase inhibitors in the form of their salts, characterized in that the corresponding precursors of the actual active substances with bases containing alkali or alkaline earth ions are converted into the active substance in a solvent and that the solution containing active substances thus arising is further processed into the desired application form.
L'invention concerne un procédé pour la fabrication de médicaments contenant des inhibiteurs de la HMG-CoA-réductase sous forme de leurs sels, caractérisé en ce que l'on transforme en principe actif dans un solvant les progéniteurs correspondants des principes actifs proprement dits avec des bases renfermant des ions alcalins ou alcalino-terreux et en ce que l'on transforme ultérieurement en la forme d'administration souhaitée la solution ainsi obtenue contenant le principe actif.
Geisen Karl
Pollinger Norbert
Samaan Samir
Schuckler Fritz
Aktiengesellschaft Bayer
Fetherstonhaugh & Co.
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