Method for producing natural diol-1,3 derivatives and...

C - Chemistry – Metallurgy – 12 – P

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C12P 17/06 (2006.01) C07D 319/06 (2006.01) C12P 7/18 (2006.01) A61K 7/46 (1995.01)

Patent

CA 2260853

The invention concerns a method for the biosynthesis of natural diol -1,3 derivatives of general formula (I) in which Z is the pentyl or pent-2-enyl (Z) or (E), preferably (Z) grouping, which consists in converting a natural precursor of said diols by means of one enzymatic complex and optional separation of the diols-1,3 obtained. The invention also concerns a method for the synthesis of natural 1,3- dioxanes structure compounds by spontaneous acetalisation of the diols-1,3 obtained by the above biosynthesis method. Finally the invention concerns any aromatic composition containing the natural 1,3-dioxane structure compounds thus prepared.

L'invention concerne un procédé de biosynthèse des dérivés de diol-1,3 naturels de formule générale (I) dans laquelle Z est le groupement pentyle ou pent-2-ényle (Z) ou (E), de préférence (Z), qui consiste en la conversion d''un précurseur naturel desdits diols à l'aide d'un complexe enzymatique et séparation éventuelle des diols-1,3 obtenus. L'invention concerne également un procédé de synthèse de composés de structure 1,3-dioxane naturels obtenus par acétalisation spontanée des dérivés de diol-1,3 obtenus par le procédé de biosynthèse précité. Enfin, l'invention concerne toute composition aromatique contenant les composés de structure 1,3-dioxane naturels ainsi préparés.

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