Method for producing optically active compound

Details Method for producing optically active compound Method for producing optically active compound

C - Chemistry, Metallurgy

12

N

C12N 15/70 (2006.01) C12N 1/21 (2006.01) C12N 15/60 (2006.01) C12P 17/10 (2006.01) C12P 41/00 (2006.01) C07D 207/16 (2006.01) C12N 9/88 (2006.01)

Patent

CA 2633357

The present invention provides a method for industrially advantageously producing (S)-4-hydroxy-2--ketoglutaric acid and for producing compounds which are formed by biosynthesis from the precursor (S)-4-hydroxy-2--ketoglutaric acid, for example, for producing the compounds (2S,4S)-4-hydroxy-L-glutamic acid and (2S,4S)-4-hydroxy-L--proline, using a recombinant microorganism carrying a recombinant DNA harboring the DNA fragment encoding 4(S)-4--hydroxy-2-ketoglutaric acid aldolase gene.

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