Method for producing peptide libraries and use thereof

Details Method for producing peptide libraries and use thereof Method for producing peptide libraries and use thereof

G - Physics

06

F

G06F 19/24 (2011.01) A61K 38/17 (2006.01) A61K 38/22 (2006.01) C07K 14/575 (2006.01) C40B 30/02 (2006.01) C40B 40/10 (2006.01) C40B 50/02 (2006.01)

Patent

CA 2680766

Screening of peptide libraries in various assays offers the possibility of simultaneously examining intracellular signal pathways, producing reagents for a better understanding of the pathway and for producing novel forms of therapy. Many, if not all, of the biologically active peptides (e.g. peptide hormones) have a great effect on health and on illnesses, either in growth-promoting rolls, growth-inhibiting rolls or by controlling the critical metabolic pathway. The invention relates to novel bioactive peptides, to an in silicio method for identifying said peptides and to a peptide library containing said peptides.

Le criblage de bibliothèques peptidiques dans divers dosages biologiques offre la possibilité de réaliser simultanément l'examen de voies de signalisation intracellulaires, la production de réactifs pour une meilleure compréhension de la voie, et la production de nouvelles formes thérapeutiques. De nombreux peptides biologiquement actifs (par ex. des hormones peptidiques), voir tous, ont des effets importants sur la santé et sur la maladie, dans des rôles de stimulation de la croissance ou d'inhibition de la croissance, ou par régulation de voies métaboliques critiques. L'invention concerne de nouveaux peptides biologiquement actifs, un procédé in silicio d'identification de ces peptides et une bibliothèque peptidique contenant ces peptides.

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