Method for producing protein-synthetic polymer conjugate and...

C - Chemistry – Metallurgy – 07 – K

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C07K 14/00 (2006.01) C07K 1/107 (2006.01) C07K 17/08 (2006.01) C08F 289/00 (2006.01) C08F 290/08 (2006.01) C08G 18/64 (2006.01) C08G 59/04 (2006.01) C08G 81/00 (2006.01) C08G 83/00 (2006.01) C08H 1/00 (2006.01)

Patent

CA 2119232

- 21 - ABSTRACT A method for producing an ester of a protein by the esterification reaction of a protein in the form of aqueous solution, fine powder or suspension with an excess amount of polyfunctional alcohol to lengthen the chain of the side chain carboxyl group of the protein; a method for producing a protein-synthetic polymer conjugate from said ester by utilizing the hydroxyl or unsaturated group of the polyfunctional alcohol present in the lengthened side chain; and a protein-synthetic polymer conjugate produced thereby.

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