Method for producing pyrazole fused ring derivative

Details Method for producing pyrazole fused ring derivative Method for producing pyrazole fused ring derivative

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 25/22 (2006.01) A61P 25/24 (2006.01) A61P 43/00 (2006.01) C07F 5/02 (2006.01)

Patent

CA 2702958

Disclosed is a commercially advantageous method for producing a pyrazole fused ring derivative (such as a 7-phenylpyrazolo[1,5-a]pyridine derivative). Specifically disclosed is a method for producing a compound (I) represented by the formula (I) below or a salt thereof, which comprises a step A wherein a hydroxy group in a compound (IV) represented by the formula (IV) below is converted into a methoxy group, thereby obtaining a compound (I) or a salt thereof: (see formula I) (see formula IV).

La présente invention concerne un procédé commercialement avantageux de production d'un dérivé de pyrazole à cycles fusionnés (tel qu'un dérivé de 7-phénylpyrazolo[1,5-a]pyridine). L'invention concerne spécifiquement un procédé de production d'un composé (I) représenté par la formule (I) ci-dessous ou un sel de celui-ci, qui comprend une étape A dans laquelle un groupe hydroxy dans un composé (IV) représenté par la formule (IV) ci-dessous est converti en un groupe méthoxy, obtenant de ce fait un composé (I) ou un sel de celui-ci.

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