Method for producing recombinant adenovirus

C - Chemistry – Metallurgy – 12 – N

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C12N 7/01 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C12N 7/02 (2006.01) C12N 15/86 (2006.01) C12N 15/861 (2006.01) G01N 30/02 (2006.01)

Patent

CA 2258158

The invention concerns a method for producing recombinant adenovirus by which viral DNA is introduced in a packaging cell culture and the viruses produced are harvested after liberation in the supernatant. The invention also concerns the viruses produced and their use.

L'invention concerne un procédé pour la production d'adénovirus recombinants selon lequel l'ADN viral est introduit dans une culture de cellules d'encapsidation et les virus produits sont récoltés après libération dans le surnageant. Elle concerne également les virus produits et leur utilisation.

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