Method for producing recombinant immunoglobulins

Details Method for producing recombinant immunoglobulins Method for producing recombinant immunoglobulins

C - Chemistry, Metallurgy

12

P

195/1.34, 150/8.

C12P 21/00 (2006.01) C07K 16/46 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2034553

JLT 4Y 18063Y TITLE OF THE INVENTION METHOD FOR PRODUCING RECOMBINANT IMMUNOGLOBULINS ABSTRACT OF THE DISCLOSURE A method for producing recombinant immunoglobulins in which the unique complementarity determining regions of immunoglobulins from a first animal monoclonal antibody are inserted by recombinant technology into a uniquely selected framework of a second animal, including humans. The recombinant DNA constructs of the invention can be used to transfect cells which will produce the recombinant immunoglobulins.

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