Method for producing substituted pyridine derivatives

Details Method for producing substituted pyridine derivatives Method for producing substituted pyridine derivatives

C - Chemistry, Metallurgy

07

D

C07D 213/61 (2006.01) C07D 213/127 (2006.01) C07D 213/26 (2006.01)

Patent

CA 2067860

ABSTRACT A method for producing a substituted pyridine derivative of the formula (II): Image (II) wherein each of R1, R2, R3 and R4 is a hydrogen atom, a halogen atom or an alkyl group, and m is an integer of from 1 to 3, which comprises reducing a substituted trichloromethylpyridine derivative of the formula (I): Image (I) wherein R1, R2, R3 and R4 are as defined above, with use of acetic acid, hydrochloric acid or sulfuric acid, as a proton donor, and zinc, tin or a mixture thereof, as a reducing agent.

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