Method for producing synthetic n-linked glycoconjugates

Details Method for producing synthetic n-linked glycoconjugates Method for producing synthetic n-linked glycoconjugates

C - Chemistry, Metallurgy

07

K

C07K 9/00 (2006.01) A61K 47/48 (2006.01) C07K 1/10 (2006.01)

Patent

CA 2080502

07-27(904)A METHOD FOR PRODUCING SYNTHETIC N-LINKED GLYCOCONJUGATES Abstract of the Disclosure A method is disclosed for derivatizing oligosaccharides to form synthetic N-linked glycoconjugates by converting a glycosylamine derivative of the oligosaccharide to a haloacetylated derivative as an intermediate compound prior to formation of the synthetic N-linked glycoconjugate to thereby directly maintain the .beta.-anomeric configuration of said N-linked glycoconjugate.

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