Method for producing th-independent cytotoxic t lymphocytes

Details Method for producing th-independent cytotoxic t lymphocytes Method for producing th-independent cytotoxic t lymphocytes

C - Chemistry, Metallurgy

12

N

C12N 5/10 (2006.01) A61K 35/14 (2006.01) A61K 35/18 (2006.01) C07K 14/715 (2006.01) C12N 5/06 (2006.01) C12N 15/25 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2092548

2092548 9205794 PCTABS00011 The present invention relates to cytotoxic T lymphocytes (CTLs) which have been converted to a helper T cell independent phenotype by introducing a recombinant expression vector encoding IL-1 receptor into the CTL. The resulting CTLs have the ability to grow or function independent of T cell help.

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