Method for production of 1-alkyl-3-phenyluracils

C - Chemistry – Metallurgy – 07 – D

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C07D 239/54 (2006.01)

Patent

CA 2609050

The invention relates to a method for production of 1-alkyl-3- phenyluracils of formula (I), where the variables R1 to R7 have the meanings given in the description, whereby 3-phenyluracils of formula (II) and alkylating agents of formula (III) are reacted together, characterised in that during the complete reaction the pH is maintained in the range of 1 to 6 by portioned addition of base.

L'invention concerne un procédé pour produire des 1-alkyl-3-phényluraciles de formule (I), dans laquelle les variables R1 à R7 ont les significations indiquées dans la description. Selon l'invention, des 3-phényluraciles de formule (II) et des agents d'alkylation de formule (III) sont mis à réagir ensemble. L'invention est caractérisée en ce que pendant toute la durée de la réaction, le pH est maintenu entre 1 et 6 par addition de bases de manière dosée.

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