Method for production of a preparation of a solid...

A - Human Necessities – 61 – K

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Details

A61K 9/107 (2006.01) A61K 47/20 (2006.01) A61K 47/24 (2006.01) A61P 19/00 (2006.01) A61P 35/04 (2006.01) A61P 39/06 (2006.01)

Patent

CA 2599121

The invention relates to a method for production of an oral, rectal or vaginal preparation comprising a solid silicone oil emulsion, characterised in that said preparation comprises 0.01 - 85 wt. % dimethicone and 0.01 - 45 wt. % dimethylsulphoxide, whereby the preparation dissolves after application and the emulsion is released. The dimethylsulphoxide is then resorbed and the remaining components of the preparation remain in the gut or vagina as a result of the molecular size thereof and subsequently are totally deposited. The invention further relates to a preparation and a method for production of a preparation made from a silicone oil emulsion.

L'invention concerne un procédé de fabrication d'une préparation orale, rectale ou vaginale contenant une émulsion d'huile de silicone solide. Le procédé selon l'invention est caractérisé en ce que la préparation contient 0,01 à 85 % en poids de diméthicone et 0,01 à 45 % en poids de diméthylsulfoxyde. Après application, la préparation se dissout et l'émulsion est libérée, le diméthylsulfoxyde est résorbé et les résidus de la préparation restent contenus dans l'intestin ou le vagin en raison de la taille des molécules, et sont ensuite éliminés complètement. L'invention concerne également une préparation et un procédé de fabrication d'une préparation à base d'une émulsion d'huile de silicone.

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