C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 231/12 (2006.01) C07C 233/09 (2006.01) C07D 207/38 (2006.01)
Patent
CA 2531603
The invention relates to a method for production of .alpha.,.beta.-unsaturated amide compounds of general formula (I): whereby (A) a protective group is introduced into a molecule of general formula (II) to give a compound of formula (III), (B) the compound obtained is reacted in the presence of (i) a dehydrogenation catalyst and (ii) a suitable oxidation agent and (C) the protective groups are removed.
L'invention concerne des procédés permettant de produire des composés amide .alpha.,.beta.-insaturés de formule générale (I), (B) par insertion, dans un composé de formule générale (II), de groupes protecteurs, de sorte à créer un composé de formule générale (III) ; (B) par réaction du composé obtenu en présence (i) d'un catalyseur de déshydrogénation et (ii) d'un agent d'oxydation approprié, et (C) par élimination des groupes de protection.
Mueller Beat W.
Schaerer Norbert
Weber Beat
Siegfried Generics International Ag
Smart & Biggar
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