Method for production of cephalosporin compounds

C - Chemistry – Metallurgy – 07 – D

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

260/103, 260/108

C07D 501/16 (2006.01) C07F 9/6571 (2006.01) C07F 9/6574 (2006.01)

Patent

CA 1219856

ABSTRACT A novel method of producing a cephalosporin compound of the formula Image [I] wherein R1 is a hydrogen atom or an acyl group; R is a hydrogen atom or an ester residue; the dotted line means a double bond in 2- or 3-position of the cephem ring; and R4 is a nucleophilic compound residue, or a salt thereof, directly in one step from a compound of the formula Image [II] wherein R1, R and the dotted line have the meanings defined above, or a salt thereof, by reacting in the presence of an organic solvent the compound [II] or a salt thereof, a nucleophilic compound or a salt thereof, and (1) a trivalent or cyclic phosphorus compound having a partial structure of the formula Image wherein W is an oxygen atom, a sulfur atom or NR2; W1 is an oxygen atom, a sulfur atom or NR3; and R2 and R3 may be the same or different and each means a hydrogen atom or a hydrocarbon group, or a salt thereof, or (2) a reaction product of a compound having a partial structure of the formula Image wherein W and W1 have the same meanings as defined above, or a salt thereof, with a phosphorus oxyhalide, trihalide or Cephalosporin compounds [I] provide valuable antimicrobial compounds and are also important intermediate compounds for the production of such cephalosporin compounds.

411185

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Method for production of cephalosporin compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for production of cephalosporin compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for production of cephalosporin compounds will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1318083

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.