Method for production of single- and multi-layer microcapsules

B - Operations – Transporting – 01 – J

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Details

B01J 13/12 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) B01J 13/06 (2006.01) B01J 13/22 (2006.01)

Patent

CA 2620026

The present invention provides methods for microencapsulation of active ingredients for topical application, whereby single-layer and multi-layer, preferably double-layer, microcapsules, are obtained. The microcapsules protect the active ingredients, maintain their original activity throught processing, formulation and storage, and enable controlled release of the active ingredient only upon application onto the skin. The microcapsules consist of a cone made of an encapsulated active ingredient and one or more shells of the same of different wall-forming polymer. The microencapsulation methods of the present invention are based on the solvent removal method.

L'invention concerne des procédés de microencapsulation d'ingrédients actifs destinés à l'application topique, qui permettent de produire des microcapsules comprenant une ou plusieurs couches, et de préférence deux couches. Ces microcapsules protègent les ingrédients actifs, préservent leur activité d'origine au cours du traitement, de la préparation et du stockage, et permettent la libération contrôlée des ingrédients actifs seulement après l'application sur la peau.

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