Method for production of substance in candida utilis using...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/09 (2006.01) C12N 1/19 (2006.01) C12P 7/56 (2006.01)

Patent

CA 2761877

Disclosed are Candida utilis yeast lines that have been transformed with at least one of three kinds of genes that have been mechanically linked to a promoter sequence and code for polypeptides that have xylose reductase, xylitol dehydrogenase and xylulose phosphorylase activity. Said yeast lines are useful for manufacturing metabolic products from xylose with high efficiency.

La présente invention concerne des lignées de levure de Candida utilis qui ont été transformées avec au moins l'un de trois types de gènes qui ont été mécaniquement liés à une séquence de promoteur et codent pour des polypeptides qui ont une activité xylose réductase, xylitol déshydrogénase et xylulose phosphorylase. Lesdites lignées de levure sont utiles pour fabriquer des produits métaboliques à partir du xylose avec une efficacité élevée.

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