A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/495 (2006.01) A61K 31/195 (2006.01) A61K 31/34 (2006.01) A61K 31/341 (2006.01) A61K 31/40 (2006.01) A61K 31/402 (2006.01) A61K 31/44 (2006.01) A61K 31/455 (2006.01)
Patent
CA 2208485
A therapeutic and prophylactic method for protection of heart or heart tissue by limiting metabolic and ionic abnormalities developed during, following or associated with ischemia by administering to a subject in need either a compound which reduces NADH/NAD+ ratio and stimulates glycolysis to produce ATP or a compound which inhibits cotransporter of sodium-potassium-chloride.
L'invention concerne un traitement effectué à titre préventif et curatif pour protéger le coeur ou le tissu cardiaque, consistant à réduire les anomalies métaboliques ou ioniques qui se développent durant ou après une ischémie ou qui sont associées à celle-ci, en administrant au patient soit un composé qui diminue le rapport NADH/NAD?+¿ et qui stimule la glycolyse pour produire de l'ATP, soit un composé qui inhibe le co-transporteur du chlorure de sodium et du chlorure de potassium.
Ramasamy Ravichandran
Schaefer Saul
Gowling Lafleur Henderson Llp
The Regents Of The University Of California
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