Method for purification of antibodies

A - Human Necessities – 61 – K

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167/139, 195/1.1

A61K 39/395 (2006.01) C07K 16/06 (2006.01) C12P 21/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1323567

ABSTRACT OF THE DISCLOSURE I(g)G3 antibody is purified by affinity chromato- graphy and collection of released antibody at a pH of 9.0 to 9.6. The purification is effected in a column containing both an affinity matrix and a desalting matrix, with the column being equilibrated to a pH of from 9.0 to 9.6. I(g)G3 antibody may be stored at pH 9.0 to 9.6.

548559

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