Method for purification of hepatitis b virus surface antigen

Details Method for purification of hepatitis b virus surface antigen Method for purification of hepatitis b virus surface antigen

A - Human Necessities

61

K

167/130

A61K 39/29 (2006.01) C07K 14/02 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1216790

- 1 - Abstract: The invention provides an improved method for the purification of hepatitis B virus surface antigen by column chromatography. The gel used for the chroma- tography is a sulfuric acid ester of a crosslinked polysaccharide or cellulose which is obtained by sulfating a crosslinked polysaccharide or cellulose. The method can give a highly purified hepatitis B virus surface antigen which is useful for the preparation of hepatitis B virus vaccine.

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