Method for purification of japanese encephalitis virus

C - Chemistry – Metallurgy – 12 – N

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C12N 7/02 (2006.01) A61K 39/12 (2006.01)

Patent

CA 1251400

Abstract of Disclosure Disclosed is an improved method for the purifi- cation of Japanese encephalitis virus, which comprises subjecting a solution containing the Japanese encephalitis virus to column chromatography using, as a gel for chromato- graphy, a sulfuric acid ester of cellulose or a crosslinked polysaccharide. The method can provide highly purified Japanese encephalitis virus, which is useful for obtaining an effective vaccine against Japanese encephalitis.

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