C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 203/04 (2006.01)
Patent
CA 2705634
The present invention relates to a method for purifying naproxcinod comprising the steps of : a) dissolving or dispersing a mixture containing naproxcinod in an amount higher than 90% by weight in a solvent; b) cooling the solution or two phases dispersion under stirring to a temperature ranging from -20°C to 10°C c) optionally seeding the solution with crystals of naproxcinod d) stirring, by maintaining the temperature in the range from - 40°C to 10°C e) collecting the formed solid by maintaining the temperature under 15°C A further object of the invention is a crystalline form of naproxcinod.
La présente invention concerne un procédé de purification de naproxcinod comprenant les étapes de : a) dissolution ou dispersion d'un mélange contenant du naproxcinod en une quantité supérieure à 90 % en poids dans un solvant; b) refroidissement de la solution ou de la dispersion à deux phases sous agitation à une température comprise entre -20 °C et 10 °C, c) en option, ensemencement de la solution avec des cristaux de naproxcinod, d) agitation, en maintenant la température dans l'intervalle de -40 °C à 10 °C, e) collecte du solide formé en maintenant la température en dessous de 15 °C. Un autre objet de l'invention concerne une forme cristalline de naproxcinod.
Allegrini Pietro
Delahaique. Thierry
Rivolta Romano
Scubla Tiziano
Toniutti Nicoletta
Gowling Lafleur Henderson Llp
Nicox S.a.
LandOfFree
Method for purifying 4-(nitrooxy)butyl... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method for purifying 4-(nitrooxy)butyl..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for purifying 4-(nitrooxy)butyl... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1838641