A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 35/14 (2006.01) A61K 35/18 (2006.01) A61L 2/00 (2006.01) A61P 7/00 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2435848
The invention is based on the discovery of a method for removing an analyte from blood cells that results in a preparation of blood cells in which the level of the residual analyte is significantly reduced in the cell population. The method can be performed on large volume blood cell suspensions, and the cells prepared in this manner remain viable following prolonged storage and are suitable for therapeutic use, e.g. in transfusion applications. A preferred blood cell preparation is one that includes a red blood cell (RBC) population.
La présente invention repose sur la découverte d'un procédé permettant d'éliminer un analyte à partir des cellules sanguines qui aboutit à une préparation de cellules sanguines dans laquelle le niveau d'analyte résiduel est considérablement réduit dans la population cellulaire. Le procédé peut être mis en oeuvre sur un important volume de suspensions de cellules sanguines, et les cellules sanguines ainsi préparées demeurent viables suite à un stockage prolongé et sont aptes à une utilisation thérapeutique, par exemple dans des transfusions. Une préparation de cellules sanguines préférée est celle qui comprend une population de globules rouges (GR).
Chapman John
Hope James
Pages Etienne
Purmal Andrei
Haemonetics Corporation
Smart & Biggar
V.i. Technologies Inc.
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