Method for purifying .alpha.-l-aspartyl-l-phenylalanine...

C - Chemistry – Metallurgy – 07 – K

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530/5.06

C07K 5/072 (2006.01)

Patent

CA 1148943

ABSTRACT OF THE DISCLOSURE: A method for purifying an .alpha.-L-aspartyl-L- phenylalanine lower alkyl ester containing impurities. The .alpha.-L-aspartyl-L-phenylalanine lower alkyl ester is brought into contact with a C1-type anion exchange resin in an aqueous medium to have the impurities adsorbed by the anion exchange resin. The impurities contained in the .alpha.-L-aspartyl-L-phenylalanine lower ester, particularly diketopiperazine and .alpha.-L-aspartyl-L- phenylalanine are selectively and easily removed. The desired matter thus can be easily recovered and disposal of waste liquid, etc. can also be carried out without difficulty.

349450

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