Method for purifying an outer membrane protein of...

Details Method for purifying an outer membrane protein of... Method for purifying an outer membrane protein of...

C - Chemistry, Metallurgy

12

P

195/128.1, 530/3

C12P 21/06 (2006.01) A61K 39/102 (2006.01) C07K 14/285 (2006.01)

Patent

CA 2012676

RFP:416B US A METHOD FOR PURIFYING AN OUTER MEMBRANE PROTEIN OF HAEMOPHILUS INFLUENZAE ABSTRACT OF THE DISCLOSURE A method of purifying an immunogenic outer membrane protein of H. flu. The steps comprising, formation of an insoluble fraction comprising the outer membrane protein associated with the peptidoglycan from the H. flu; digesting contaminated RNA from the insoluble fraction; separating the outer membrane protein from the insoluble fraction into the supernatant; and concentrating the solubilized outer membrane protein.

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